dimethyl acetamide toxicity

Acetamide, N,N-dimethyl- Material Safety Data Sheet

toxicity (LD50): 4300 mg/kg [Rat]. Acute dermal toxicity (LD50): 2240 mg/kg [Rabbit]. Acute toxicity of the vapor (LC50): 2475 1 hours [Rat]. Chronic Effects on Humans: Causes damage to the following organs: liver, central nervous system (CNS). May cause damage to the following organs: kidneys, skin. Other Toxic Effects on Humans:

DIMETHYL ACETAMIDE HAZARD SUMMARY - New Jersey

Dimethyl Acetamide is a colorless liquid with a faint ammonia-like odor. It is used as a solvent for plastics, resins and gums. * Dimethyl Acetamide is on the Hazardous Substance List because it is regulated by OSHA and cited by ACGIH, NIOSH and NFPA. * Definitions are provided on page 5.

Some comparative toxicologic and pharmacologic effects of .

The main advantages of DMSO as a pesticide solvent when compared with other solvents, corn oil, an aqueous suspension, propylene glycol, dimethyl formamide, and dimethyl acetamide are that (a) DMSO can dissolve most pesticides in high concentrations needed for acute toxicity determination, (b) DMSO has a low toxicity in the volumes needed.

Toxicology of dimethylacetamide - ScienceDirect

TOXICOLOGY AND APPLIED PHARMACOLOGY 3, 12-24 (1961) Toxicology of Dimethylacetamide HENRY J. HORN' Hazleton Laboratories, Inc., Falls Church, ia Received February 8, 1960 Dimethylacetamide (DMA), known also as acetyldimethylamine, is a clear, neutral liquid having a specific gravity of 0.943, a boiling point of 165.5' C, and a molecular weight of 87.12.

Acetamide, N,N-dimethyl- - cdc

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO DIMETHYL ACETAMIDE-air 10H time-weighted average 10 ppm (Sk) NIOSH* DHHS #92-100,1992

N,N-DIMETHYL ACETAMIDE SOLUTION (40% OR LESS) | CAMEO .

Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]: As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above.

dimethyl acetamide toxicity,

Dimethylformamide - Wikipedia

Dimethylformamide. As its name indicates, it is a derivative of formamide, the amide of formic acid. DMF is a polar ( hydrophilic) aprotic solvent with a high boiling point. It facilitates reactions that follow polar mechanisms, such as SN2 reactions.

2,4-D - toxicity, ecological toxicity and regulatory .

2,4-D - Identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information Note : See Working with the Information on this Page section below for …

MSDS TOXICITY Acetamide, thio-N,N-dimethyl-2,2-diphenyl .

Acetamide, thio-N,N-dimethyl-2,2-diphenyl- MSDS. Search MSDS : Acetamide, thio-N,N-dimethyl-2,2-diphenyl- . Intraperitoneal SPECIES OBSERVED: Rodent - mouse DOSE / DURATION: 250 mg/kg TOXIC EFFECTS: Details of toxic effects not reported other than lethal dose value REFERENCE: Formerly U.S. Clearinghouse for Scientific & Technical Information. .

DIMETHYLACETAMIDE | CAMEO Chemicals | NOAA

The Hazard fields include special hazard alerts, air and water reactions, fire hazards, health hazards, a reactivity profile, and details about reactive groups assignments and potentially incompatible absorbents.The information in CAMEO Chemicals comes from a variety of data sources.

2,4-D - toxicity, ecological toxicity and regulatory .

2,4-D - Identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information Note : See Working with the Information on this Page section below for …

N,N-DIMETHYL ACETAMIDE For HPLC MSDS | CAS 127-19-5 …

MATERIAL SAFETY DATA SHEET (MSDS) .lobachemie 27/05/2016 1/9 N,N-DIMETHYL ACETAMIDE FOR HPLC MSDS CAS-No.: 127-19-5 MSDS SECTION 1: Identification of the substance/mixture and of the company/undertaking

N,N-Dimethylacetamide | C4H9NO | ChemSpider

Toxicity: ORL-RAT LD50 5090 mg kg-1, IPR-RAT LD50 2750 mg kg-1, ORL-MUS LD50 4260 mg kg-1, . A member of the class of acetamides that is acetamide in which the hydrogens attached to the N atom have been replaced by two methyl groups respectively. Metabolite observed in cancer metabolism.

N,N-Dimethyl Acetamide

Specific target organ toxicity - single exposure No data available Specific target organ toxicity - repeated exposure No data available Aspiration hazard No data available Additional Information RTECS: AB7700000 impaired judgment, emotional instability, toxic psychosis, nystagmus, dysarthria, Ataxia.

Dimethylacetamide - Wikipedia

Toxicity Dimethylacetamide is a medium potency reproductive toxicant ( toxic for reproduction, category 1B) [8] and may damage fertility or the unborn child. It is harmful in contact with skin or if inhaled, and causes serious eye irritation.

N,N-Dimethylacetamide | C4H9NO | ChemSpider

Toxicity: ORL-RAT LD50 5090 mg kg-1, IPR-RAT LD50 2750 mg kg-1, ORL-MUS LD50 4260 mg kg-1, IVN-MUS LD50 3020 mg kg-1 Oxford University Chemical Safety Data …

Developmental toxicity of dimethylacetamide by inhalation .

FUNDAMENTAL AND APPLIED TOXICOLOGY 16, 414-422 (1991) Developmental Toxicity of Dimethylacetamide by Inhalation in the Rat' HOWARD M. SOLOMON,Z RAYANNE L. FERENZ, GERALD L. KENNEDY, JR., AND ROBERT E. STAPLES3 Central Research and Development Department, E. I. duPont de Nemours and Company, Inc., Haskell Laboratory, Newark, Delaware …

Acetone - Wikipedia

Acetone is believed to exhibit only slight toxicity in normal use, and there is no strong evidence of chronic health effects if basic precautions are followed. Acetone is an irritant causing mild skin irritation and moderate to severe eye irritation.

N,N-Dimethyl acetamide - toxicity, ecological toxicity and .

Acute Toxicity 2: N,N-Dimethyl acetamide WHO Acute Hazard TRI Acute Hazard Material Safety Data Sheets Acute rating from U.S. EPA product label U.S. NTP Acute Toxicity Studies View Studies Cholinesterase Inhibitor: Not Listed Not Listed Not Available No Consensus Value No NTP Studies No 2.

Dimethylacetamide - WikiVisually

Toxicity Dimethylacetamide is a medium potency reproductive toxicant ( toxic for reproduction, category 1B) [7] and may damage fertility or the unborn child. It is harmful in contact with skin or if inhaled, and causes serious eye irritation.

dimethyl acetamide toxicity,

N,N-Dimethylacetamide | C4H9NO | ChemSpider

Toxicity: ORL-RAT LD50 5090 mg kg-1, IPR-RAT LD50 2750 mg kg-1, ORL-MUS LD50 4260 mg kg-1, IVN-MUS LD50 3020 mg kg-1 Oxford University Chemical Safety Data …

N,N-dimethyl acetamide, 127-19-5 - The Good Scents Company

Dermal Toxicity: skin-mouse LD50 9600 mg/kg LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES LIVER: OTHER CHANGES BEHAVIORAL: FOOD INTAKE (ANIMAL) Zhonghua Yufangyixue Zazhi. Chinese Journal of Preventive Medicine. Vol. 13, Pg. 29, 1979. skin-rabbit LD50 2240 mg/kg SKIN AND APPENDAGES (SKIN): PRIMARY IRRITATION: AFTER TOPICAL EXPOSURE

N,N-Dimethylacetamide | 127-19-5

N,N-dimethylacetamide dimethyl amine, also known as an acetyl group, an acetyl dimethylamine, referred to as the DMAC, which is a highly polar aprotic solvent, micro ammonia odor, very strong dissolving power, soluble wide, miscible with water, aromatics, esters, ketones, alcohols, ether, benzene and chloroform and other arbitrary and enable activation of molecular compounds.

Dimethylacetamide Explained

Toxicity. Dimethylacetamide is a medium potency reproductive toxicant (toxic for reproduction, category 1B) and may damage fertility or the unborn child. It is harmful in contact with skin or if inhaled, and causes serious eye irritation.

DIMETHYLACETAMIDE MSDS & SPECS - MANAV CHEM

chlorinated and aromatic solvents except aliphatic hydrocarbons. DMAc is produced from acetic acid and dimethylamine. It is the acetic acid amide with two methyl group substituents on the nitrogen atom. The is formic acid analogue is N,N,-dimethylformamide (DMF). DMAc is less toxic …

Acetamide | CH3CONH2 - PubChem

Acetamide has low acute toxicity in laboratory animals; decreased body weight was the only toxic effect associated with a single exposure to a very high oral dose. Liver tumors and lymphoma were observed in laboratory animals following repeated oral exposure to acetamide over time.

DIMETHYL ACETAMIDE HAZARD SUMMARY - New Jersey

* Dimethyl Acetamide may damage the liver causing nausea and/or jaundice. IDENTIFICATION Dimethyl Acetamide is a colorless liquid with a faint ammonia-like odor. It is used as a solvent for plastics, resins and gums. REASON FOR CITATION * Dimethyl Acetamide is on the Hazardous Substance List because it is regulated by OSHA and cited by ACGIH,

Pharmacological actions and toxicity of dimethyl .

Dimethyl sulphoxide and other non‐electrolytes have been shown to protect partially, the smooth muscle of the guinea‐pig uterus from damage during freezing to and thawing from –79°. The mechanism of this protection is probably physico‐chemical in nature, for none of the compounds had any specific pharmacological action on smooth muscle.

Acute and subchronic toxicity of dimethylformamide and .

Acute and subchronic toxicity of dimethylformamide and dimethylacetamide following various routes of administration. Kennedy GL Jr, Sherman H. Dimethylformamide (DMF, CAS No. 68-12-2) and dimethylacetamide (DMAC, CAS No. 127-19-5) are widely used for their superior solvent properties.

dimethyl acetamide toxicity,

Acetamide, N,N-dimethyl- Material Safety Data Sheet

DEVELOPMENTAL TOXICITY: Not available. The substance is toxic to liver, central nervous system (CNS). The substance may be toxic to kidneys, skin. Repeated or prolonged exposure to the substance can produce target organs damage. Section 4: First Aid Measures