ethyl acetate toxicity in humans

ethyl acetate toxicity in humans,

Ethyl acetate - Wikipedia

Safety. Overexposure to ethyl acetate may cause irritation of the eyes, nose, and throat. Severe overexposure may cause weakness, drowsiness, and unconsciousness. Humans exposed to a concentration of 400 ppm in 1.4 mg/L ethyl acetate for a short time were affected by nose and throat irritation.

Physiologically based pharmacokinetic modeling of ethyl .

The human ethyl acetate inhalation exposure concentration (ppm) resulting in an arterial blood ethyl acetate AUC (mM × h) or blood ethanol AUC matching the blood ethyl acetate AUC or blood ethanol AUC in the rat following LOAEL concentration exposure (6 h/day, 5 days/week) is termed the human equivalent concentration (HEC).

Physiologically based pharmacokinetic modeling of ethyl .

Ethyl acetate is metabolized to ethanol in the blood, liver and other perfused tissues, reflecting significant extrahepatic metabolism ( Deisinger and English, 2003 ). Ethanol is metabolized (cleared from the model) in the liver, other perfused tissues (rat), and richly perfused tissues (human).

Acetic Acid Ethyl Ester - an overview | ScienceDirect Topics

Summary: Ethyl acetate appears to be non-irritant and non-allergenic, and has minimal oral toxicity. The US inhalational threshold limit is 400 ppm. The US inhalational threshold limit is 400 ppm. Regulatory guidelines: In 1973 an inhalational threshold limit value for ethyl acetate was set at 400 ppm by the US Governmental Industrial Hygienists.

Safety Data Sheet - Fisher Scientific

Safety Data Sheet according to 29CFR1910/1200 and GHS Rev. 3 Effective date : 11.19.2014 Page 2 of 8 Ethyl Acetate Created by Global Safety Management, Inc. -Tel: 1-813-435-5161 - .gsmsds

Ethyl Acetate.pdf - He alth 3 Science Lahmm 3 1 Chemicals .

Other Toxic Effects on Humans: Hazardous in case of ingestion, of inhalation. Slightly hazardous in case of skin contact (irritant, permeator). Special Remarks on Toxicity to Animals: LD50 [Rabbit] - Route: skin; Dose >20,000 ml/kg Special Remarks on Chronic Effects on …

Ethyl Acetate: A Sweet-Smelling Safety Hazard | MSDSonline

ETHYL ACETATE | CAMEO Chemicals | NOAA

ethyl acetate toxicity in humans,

Ethyl acetate - toxicity, ecological toxicity and .

Ethyl acetate - Identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information Note : See Working with the Information on this …

Ethyl acetate | CH3COOC2H5 - PubChem

Ethyl acetate is a volatile compound that is in wines, brandy, fruits like pineapple and essential oils obtained from fruits and flowers. It is formed in the process of fermenting beers. Ethyl acetate is found in many foods such as kiwi fruit, guava fruit, roasted filberts, blue cheese and baked potatoes.

SAFETY DATA SHEET: ETHYL ACETATE - ciscochem

Other Toxic Effects on Humans: Hazardous in case of ingestion, of inhalation. Slightly hazardous in case of skin contact (irritant, permeator). . Ethyl acetate Illinois toxic substances disclosure to employee act: Ethyl acetate Illinois chemical safety act: Ethyl acetate New York release reporting list: Ethyl acetate Rhode Island RTK .

Material Safety Data Sheet - Harper College

Ethyl acetate 141-78-6 100 Toxicological Data on Ingredients: Ethyl acetate: ORAL (LD50): Acute: 5620 mg/kg [Rat]. 4100 mg/kg [Mouse]. 4935 mg/kg [Rabbit]. VAPOR (LC50): Acute: 45000 mg/m 3 hours [Mouse]. 16000 ppm 6 hours [Rat]. Section 3: Hazards Identification Potential Acute Health Effects: Hazardous in case of ingestion, of inhalation.

ethyl acetate toxicity in humans,

What Are the Dangers of Ethylene Vinyl Acetate .

Ethylene vinyl acetate is a type of plastic — a polymer with a wide variety of uses, both residential and industrial. The Food and Drug Administration (FDA) has stated that ethylene vinyl acetate is safe when used in food production, packaging or transportation, and it's not an especially dangerous material.

ethyl acetate | ChemHAT

Ethyl acetate. CAS: 141-78-6. How can this chemical affect my health? Acute (Short Term) EffectsData sources. Toxic to Humans & Animals – Can be fatal on contact, ingestion or inhalation for humans and other mammals. Irritates the Eyes – Can cause irritation or serious damage to the eye.

Combined Toxic Effects of Polar and Nonpolar Chemicals on .

Oct 30, 2016· We determined the toxicity of mixtures of ethyl acetate (EA), isopropyl alcohol (IPA), methyl ethyl ketone (MEK), toluene (TOL) and xylene (XYL) with half-maximal effective concentration (EC 50) values obtained using human hepatocytes cells. According to these data, quantitative property-activity relationships (QPAR) models were successfully .

Ethyl acetate - Registration Dossier - ECHA

Based on a high quality, guideline study in rats, the subchronic inhalation NOAEC for systemic toxicity of ethyl acetate is considered to be 350 ppm (1.28 mg/L), based on sedation during exposure, reduced food consumption and reduced body weight gain.

Ethyl fluoroacetate | C4H7FO2 - PubChem

ethyl fluororacetate, has ld50 of 6-10 mg/kg in mice, very similar to fluoroacetic acid. .2-fluoroethyl acetate.is only slightly less toxic, having ld50's of 18 mg/kg (these active fluoro compd have almost identical ld50's by any route or admin).

ethyl acetate toxicity in humans,

Ethyl acetate toxicity reports, review - hazard potential .

Ethyl acetate vapour was irritating to the eyes and respiratory tract of humans and various laboratory animal species. The liquid produced irritation and damage in rabbit eyes. In man, ethyl acetate has caused skin sensitization, and repeated or prolonged application may change the …

Evaluation of oral toxicity level of ethyl acetate extract .

Garlic contains compounds that are antibacterial, antiviral and antifungal. Garlic ethyl acetate extract is safe for human consumption. Keywords: Garlic, Ethyl acetate, Extract, Rats, Acute, Toxicity INTRODUCTION About 3.4 billion people in the developing world depend on plant-based traditional medicines. According to the

ethyl acetate | CAS#:141-78-6 | Chemsrc

Chemsrc provides ethyl acetate(CAS#:141-78-6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of ethyl acetate are included as well.

Ethyl Acetate Side Effects, Side Effects of Ethyl Acetate

Jul 16, 2015· Ethyl Acetate E1504 is the organic compound with the formula CH3-COO-CH2-CH3. This colorless liquid has a characteristic sweet smell similar to pears drops. It is often used primarily as a solvent and diluent, being favored because of its low cost, low toxicity, and agreeable odor. This product is commonly used in decaffeinated teas and coffees.

Ethyl acetate - Centers for Disease Control and Prevention

Basis for revised IDLH: Based on health considerations and acute inhalation toxicity data in workers [Henderson and Haggard 1943; Patty 1963], a value between 2,000 and 8,000 ppm would have been appropriate for ethyl acetate. However, the revised IDLH for ethyl acetate is 2,000 ppm based strictly on safety considerations (i.e., being 10% of the .

Safety Data Sheet - Purdue University

Ethyl acetate CAS -No. EC -No. Index -No. Registration number 141 -78 -6 205 -500 -4 607 -022 -00 -5 01 -2119475103 -46 -XXXX - 4. FIRST AID MEASURES General advice Consult a physician. Show this safety data sheet to the doctor in attendance.Move out of dangerous area. If inhaled If breathed in, move person into fresh air.

Safety Data Sheet - Purdue University

Acute toxicity, Inhalation (Category 5) Eye irritation (Category 2A) Specific target organ toxicity - single exposure (Category 3) GHS Label elements, including precautionary statements Pictogram Signal word Danger Hazard statement(s) H225 Highly flammable liquid and vapour. H319 Causes serious eye irritation. H333 May be harmful if inhaled.

Material Safety Data Sheet - University Of Maryland

Ethyl acetate ACC# 08750 Section 1 - Chemical Product and Company Identification. May be harmful if inhaled. Inhalation of high concentrations may cause narcotic effects. Chronic: Chronic inhalation may cause effects similar to those of acute inhalation. Animals exposed to …

Methyl acetate - Centers for Disease Control and Prevention

Basis for revised IDLH: Based on health considerations and acute inhalation toxicity data in humans [Clayton and Clayton 1981], the original value of about 10,000 ppm would have been appropriate for methyl acetate. However, the revised IDLH for methyl acetate is 3,100 ppm based strictly on safety considerations (i.e., being 10% of the lower .

WebWISER - Substance Data

Non-Human Toxicity Values; Ecotoxicity Values; Soil Adsorption / Mobility; Volatilization; Ethyl Acetate CAS RN: 141-78-6. Identification. Substance: Ethyl Acetate CAS RN: 141-78-6 Shipping Name/Number: UN 1173; Ethyl acetate STCC: 49 091 60; Ethyl acetate ., Health & Human Services .

Ethyl Acetate: A Sweet-Smelling Safety Hazard | MSDSonline

Apr 10, 2015· Ethyl acetate is highly flammable, as well as toxic when ingestion or inhaled, and this chemical can be seriously damaging to internal organs in the case of repeated or prolonged exposure. Ethyl acetate can also cause irritation when it comes into contact with the eyes or skin. Ethyl Acetate Safety, Handling & First Aid

Combined Toxic Effects of Polar and Nonpolar Chemicals on .

Oct 30, 2016· We determined the toxicity of mixtures of ethyl acetate (EA), isopropyl alcohol (IPA), methyl ethyl ketone (MEK), toluene (TOL) and xylene (XYL) with half-maximal effective concentration (EC 50) values obtained using human hepatocytes cells. According to these data, quantitative property-activity relationships (QPAR) models were successfully proposed to predict the toxicity of mixtures by multiple …

Ethyl acetate - Registration Dossier - ECHA - Europa

A number of other studies have reported similar or higher acute toxicity values for ethyl acetate in fish. Another study reported a 48 -hr, static LC50 value of 210 mg/L for ethyl acetate in Poecilia reticulata (Guppy), although only limited information are available about this study. One study reported a 48 -hr LC50 value of 125 mg/L for ethyl .

Evaluation of oral toxicity level of ethyl acetate extract .

Garlic contains compounds that are antibacterial, antiviral and antifungal. Garlic ethyl acetate extract is safe for human consumption. Keywords: Garlic, Ethyl acetate, Extract, Rats, Acute, Toxicity INTRODUCTION About 3.4 billion people in the developing world depend on plant-based traditional medicines. According to the